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The human health effects of poor air quality are far reaching, but principally affect the body's respiratory system and the cardiovascular system. Individual reactions to air pollutants depend on the type of pollutant a person is exposed to, the degree of exposure, the individual's health status and genetics. People who exercise outdoors, for example, on hot, smoggy days increase their exposure to pollutants in the air.

The health effects caused by air pollutants may range from subtle biochemical and physiological changes to difficulty breathing, wheezing, coughing and aggravation of existing respiratory and cardiac conditions. These effects can result in increased medication use, increased doctor or emergency room visits, more hospital admissions and even premature death.

Human Respiratory System

The health of our lungs and entire respiratory system is affected by the quality of the air we breathe. In addition to oxygen, this air contains other substances such as pollutants, which can be harmful. Exposure to chemicals by inhalation can negatively affect our lungs and other organs in the body. The respiratory system is particularly sensitive to air pollutants because much of it is made up of exposed membrane. Lungs are anatomically structured to bring large quantities of air (on average, 400 million litres in a lifetime) into intimate contact with the blood system, to facilitate the delivery of oxygen.

Lung tissue cells can be injured directly by air pollutants such as ozone, metals and free radicals. Ozone can damage the alveoli -- the individual air sacs in the lung where oxygen and carbon dioxide are exchanged. More specifically, airway tissues which are rich in bioactivation enzymes can transform organic pollutants into reactive metabolites and cause secondary lung injury. Lung tissue has an abundant blood supply that can carry toxic substances and their metabolites to distant organs. In response to toxic insult, lung cells also release a variety of potent chemical mediators that may critically affect the function of other organs such as those of the cardiovascular system. This response may also cause lung inflammation and impair lung function.